【单选题】【消耗次数：1】
疾病是指
①
细胞受损的表现
②
机体对内外环境协调功能异常
③
劳动力下降和丧失;
④
机体在一定病因作用下自稳调节紊乱而发生的异常生命活动
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【单选题】
老年人机体器官和系统功能减退，各种生理调节功能降低，代偿恢复的速度减慢，维持机体内环境平衡稳定的能力下降，对药物反应的适应性和应变能力减弱。下列说法错误的是：
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肝功能减退者，药物在体内代谢减慢，相同剂量的药物作用更强，毒副作用增加；
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肾功能减退者，药物在体内排泄延迟，相同剂量的药物作用更强，毒副作用增加；
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老年人体脂/水比例明显降低，导致水溶性药物蓄积，清除减慢；
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老年人对作用于中枢神经系统的药物更敏感，因药物相互作用导致的中枢系统毒副更严重；
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老年人体内敏感组织的结构、功能及受体部位敏感性改变，导致对药物的感受性改变；
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